English pdf, 627 kb superb foam with the pu fixed poker from basf. Poloxamer 184 poloxamer 184 is a polyoxyethylene, polyoxypropylene block polymer. As a surfactant, merge is a key requirement of great weed control. The size and structure of poloxamer assemblies, and their adsorption. Poloxamer block copolymers are non ionic surfactants available under the. In the present investigation solid dispersions with poloxamer 188 were. Ppo peoi copolymers commercially available as poloxamers and pluronics in aqueous solutions, and the adsorption of these. Basf offers wide range of excipients for topical formulations enabling you to create the ideal skin delivery solution for your foam formulation. They make this highlyefficient intermediate, used in many types of. Pluronic f127, also known as poloxamer 407, is often used in tissue.
How much merge to use merge is the only surfactant that is specially formulated to ensure maximum penetration of certain basf herbicides into weeds. Used as an emulsifying agent in intravenous fat emulsions, and as solubilizing agent to maintain the clarity of elixirs and syrups. Baroda, india and poloxamer 188 from basf corporation, mumbai, india as a gift sample. Multiblock poloxamer surfactants suppress aggregation of denatured proteins article pdf available in biochimica et biophysica acta 17801. In addition to poloxamer 188 nf, basf also offers comprehensive solutions to the pharmaceutical industry for both small and large molecule formulation needs. Merge helps you do just that, effectively optimizing your herbicide performance. Being amphiphilic also results in the ability of the individual block copolymers, known as unimers, to combine and form micelles in aqueous solutions. Basf is the first company in the world to offer triphenylphosphine tpp in the form of pellets. Merge adjuvant can be used with the following herbicides. They combine the problems of class ii and class iii drugs, and. It is a surfactant functioning both as cleansing and solubilizing agent.
For example, the preparation of p188 that is available from basf parsippany, n. Pdf dissolution rate enhancement and physicochemical. Poloxamer 188 chemical information, properties, structures, articles, patents and more chemical data. Basf is the leading manufacturer of poloxamer p 188 kolliphor p 188 with over 50 years of experience in eopo chemistry.
Basf to develop a high purity poloxamer for mast therapeutics. By extensively analyzing, refining and enhancing the sensorial effects of each ingredient class, we can help you to create products that increase patient compliance. Basf and dea agree multibillion oil and gas merger. Poloxamer 407 formulations led to enhanced solubilisation of poorly watersoluble drugs and prolonged release profile for many galenic applications e. Peroxides are transient in nature and quickly combine with butylated hydroxytoluene bht, which. Pluracare l 44 poloxamer 124 4 x 300 1200 4 x 10 40 pluracare l 64 poloxamer 184 6 x 300 1800 4 x 10 40 pluracare f 68 poloxamer 188 6 x 300 1800 8 x 10 80. Technical information pluracare lf grades poloxamer. Basf, the german chemicals group, has agreed to merge its wintershall energy unit with rival dea in a multibillioneuro deal to create one of europes largest independent oil and gas producers. Poloxamers, available also under the trademark pluronics basf, are a class of. Product and company identification company 24 hour emergency response information basf canada inc.
In particular, provided are lcmf poloxamer 188 compositions and uses thereof. White to slightly yellowish waxy substance in the form of micropearls. It is one of the most effective ways to maximize the returns on your crop protection budget. Directions for use merge adjuvant is a blend of surfactant and petroleum hydrocarbons designed for use with various herbicide sprays. Poloxamers, available also under the trademark pluronics basf, are. Refer to the herbicide label for detailed use instructions and restrictions.
Kolliphor p 407 meet the requirements of the current uspnf monographs and european pharmacopoeia family monograph poloxamer. Multiblock poloxamer surfactants suppress aggregation of. In addition, p 124 and p 188 are known to have suitable mucoadhesive force, low toxicity, less skin irritation, good drug release characteristics and. May also be used as a wetting agent in eye drops, ointments, suppository bases, gels, and. A blended surfactant designed for use with overdrive herbicides. Pluronics or poloxamers are triblock copolymers of polyethylene oxide. There are two methods involved in inducing micelle formation in a poloxamer.
In bioprocessing, poloxamer 188 has been extensively researched and has been found to be the most effective mammalian cell culture ingredient to provide shear protection during manufacturing of biologic drugs. Pdf this study investigates the potential of poloxamers as solid dispersions sds. Poloxamer hydrogels for biomedical applications mdpi. Us9403941b2 poloxamer composition free of long circulating.